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KMID : 0605720010070010112
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Journal of the Korean Society of Biological Therapies in Psychiatry
2001 Volume.7 No. 1 p.112 ~ p.119
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Novelty Seeking in Substance Use Disorder
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김미영/Mi Young Kim
박제민/윤경일/유택규/권도훈/김성군/김명정/장기용/Je Min Park/Gyung Il Yoon/Tak Gue Rue/Do Hoon Gwon/Sung Gon Kim/Myoung Jung Kim/Gi Yong Jang
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Abstract
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In this study, the relationship between substance use and high-novelty seeking was tested using Cloninger et
al's 240-items Temperament and Character Inventory(TCI) in 34 substance users(32 methamphetamine and 2 cocaine dependence disorders), 80 normal controls and 48 schizophrenice. Demographic characteristics and substance use-related past history
were
taken
by semi-structured interview. Subjects were aged 18-45 and general psychopathology was screened by Symptom Checklist 90 revised. The results were as follows.
1) Among temperament subdivision in the TCI, novelty seeking(NS) was significantly higher in the substance users(22.1±4.9) than the normal controls(18.0±5.0) and the schiaophrenics(15.6±3.3). There were no significant differences in other
temperament
subdivisions such as harm avoidance, reward dependence and
persistence, neither charecter subdivisions such as self-directiveness, cooperariveness and self-transcendence.
2) A significant inverse correlation was found between NS and age both in the substance users(r=0.274) and the normal controls(r=0.468).
This studys suggested that the biogenetic temperament characteristics in substance use disorder were related with their high novelty seeking, not low harm avoidance.
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KEYWORD
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